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Using an in vitro model reproducing filtration by the spleen, the scientists were able to identify several pharmacological agents that inhibit phosophodiesterases and can therefore increase the stiffness of infected erythrocytes. One of these agents is sildenafil citrate, better known under its brand name of Viagra. The authors showed that this agent, used at a standard dose, had the potential to increase the stiffness of sexual forms of the parasite and thus favor the elimination of infected erythrocytes by the spleen.

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Viagra (50 mg) did not potentiate the increase in bleeding time caused by aspirin (150 mg). enfermedad del corazón o problemas del ritmo cardíaco, enfermedad de la arteria coronaria;