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Several supplements are promoted for improving depression. Examples include St. John's wort, 5-hydroxytryptophan (5-HTP), SAMe, fish oil, and L-theanine. Although these supplements may have mild antidepressant properties, it is important to remember that depression is a serious condition that needs proper evaluation and treatment under the care of a physician. It is also important to note that these supplements are not regulated by the FDA; their safety and efficacy have not been proven in large clinical studies, and they may interact with other drugs.

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Common (1% to 10%): Increased glucose, anorexia, hypertriglyceridemia, decreased weight (included cachexia/wasting), weight gain, weight loss

Corynebacterium diphtheriae is grown in modified Mueller's growth medium.3 After purification by ammonium sulfate fractionation, diphtheria toxin is detoxified with formaldehyde and diafiltered. Clostridium tetani is grown in modified Mueller-Miller casamino acid medium without beef heart infusion.4 Tetanus toxin is detoxified with formaldehyde and purified by ammonium sulfate fractionation and diafiltration. Diphtheria and tetanus toxoids are individually adsorbed onto aluminum phosphate.

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