Common (1% to 10%): Cardiovascular dysfunctionTricyclic antidepressants (TCAs) are used in treating panic disorder, post-traumatic stress disorder, and general anxiety disorder. One tricyclic, clomipramine (Anafranil), may also be used to treat obsessive-compulsive disorder. Suicidal thoughts or behavior: All antidepressants may increase the risk of suicidal thoughts or behavior in children, adolescents, and young adults (18 to 24 years of age).
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seizures (convulsions), and Other than age, there are as yet no factors identified that are known to predict the risk of occurrence or the severity of rash caused by LAMICTAL. There are suggestions, yet to be proven, that the risk of rash may also be increased by (1) coadministration of LAMICTAL with valproate (includes valproic acid and divalproex sodium), (2) exceeding the recommended initial dose of LAMICTAL, or (3) exceeding the recommended dose escalation for LAMICTAL. However, cases have occurred in the absence of these factors.
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The risks and benefits of treatment with Enbrel should be carefully considered prior to initiating therapy in patients with chronic or recurrent infection.
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SIMBRINZA (brinzolamide/brimonidine tartrate ophthalmic suspension) 1%/0.2% is supplied as a sterile, aqueous suspension which has been formulated to be readily suspended following shaking. It has a pH of approximately 6.5 and an osmolality of approximately 270 mOsm/kg.
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