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HOW TO USE: Read the Medication Guide provided by your pharmacist before you start taking zonisamide and each time you get a refill. If you have any questions, consult your doctor or pharmacist. Take this medication by mouth as directed by your doctor, usually 1 to 2 times a day with or without food. Swallow the capsules whole. Do not crush or chew the capsules. To prevent kidney stones from forming, drink plenty of liquids while taking this medication unless your doctor instructs you otherwise. Dosage is based on your medical condition and response to treatment. It is very important to follow your doctor's dosing instructions exactly. Your doctor will start you on a low dose and slowly increase your dose. It may take several weeks or months to reach the best dose for you and to get the full benefit from this medication. Use this medication regularly to get the most benefit from it. This drug works best when the amount of medicine in your body is kept at a constant level. To help you remember and to keep a constant level, take zonisamide at the same time(s) each day. Do not s taking this medication without consulting your doctor. Some conditions may become worse when the drug is suddenly sped. Your dose may need to be gradually decreased. Tell your doctor if your condition does not improve or if it worsens.

Vacuolar axonopathy and hypersomnolence leading to coma and death was reported in a patient with elevated drug levels.[Ref] The Migraine TrustThey also are used for:

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If there are any noticeable changes in your vision after you started taking this drug, inform your doctor or health care professional at once. S the treatment course and inform your health care provider immediately if you are experiencing a loss of sight for one or both eyes.

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