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Rheumatoid Arthritis: The recommended dose of Celecoxib is 100 to 200 milligrams twice a day.

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The most common side effect with Sustiva (seen in more than 1 patient in 10) is rash. Sustiva is also associated with nervous system symptoms, such as dizziness, headache, somnolence (sleepiness), balance disturbances and impaired concentration, and with psychiatric disorders, including depression, anxiety, insomnia (difficulty sleeping) and abnormal dreams. Taking Sustiva with food may lead to an increase in the frequency of side effects. For a more complete list of side effects reported with Sustiva, see the package leaflet.

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HIV-1, human immunodeficiency virus type 1, a model for HIV-1 and HIV-2; PRV, pseudorabies virus, a nonspecific model for large enveloped DNA viruses (e.g., herpes virus); BVDV, bovine viral diarrhea virus, a model for hepatitis C virus; WNV, West Nile virus; EMCV, encephalomyocarditis virus, a model for hepatitis A virus; MVM, minute virus of mice, a model for a small highly resistant non-enveloped DNA virus (e.g., parvovirus); LRF, log10 reduction factor; nd, not determined; nt, not tested. Uncommon (0.1% to 1%): Affect lability, confusional state, euphoric mood, suicidal ideation, nonfatal suicide attempts, aggressive behavior, paranoid reactions, manic reactions, drug abuse

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Infliximab, the active ingredient in REMICADE, is a chimeric IgG1κ monoclonal antibody (composed of human constant and murine variable regions) specific for human tumor necrosis factor-alpha (TNFα). It has a molecular weight of approximately 149.1 kilodaltons. Infliximab is produced by a recombinant cell line cultured by continuous perfusion and is purified by a series of steps that includes measures to inactivate and remove viruses.

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